Cure for the Cancer With Prevention and Treatment in its Nascent Stage

The idea of detecting breast cancer early on comes from being aware. You need to check the changes in your bosom and take note of the signs and symptoms of breast cancer to ascertain proper and steady treatment. Nipping the disease in its bud means to know the signs of breast cancer. Once you’ve taken note the strange pain in the bosom, an inverted or flattened nipple, rashness in the region or a fluid discharge from nipple, you’re right on track for a good treatment.

Early detection and advanced mechanism have led to the launch of precision medicine initiative. The brand new and bold research and innovative effort is to revolutionize the treatment of breast cancer. Here’s how you can help yourself.

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  • Real-time cancer and diagnostics: The advanced surgical knife termed as the iKnife is the latest innovation in the world of cancer cure. Scientists have mixed an old technology of heating electrical current fiber for making incisions that create minimal blood loss. The knife entails vaporized smoke and nestles a mass sprectrometer for analyzing it to check the chemicals existing in the biological sample. It helps doctors indentify malignant and baneful tissue.
  • Channelizing the advantages: The main focus is on improving overall health and create proper treatment. There is a two-pronged strategy upholding the pledge to cure cancer, or transforming it to a treatable chronic disease. That’s the minimum thing to be done. With advanced medicines like Herceptin to treat breast cancer, the others too are creating ripples in HER-2 positive treatment. Recently, research and development have given a new biosimilar property on stage. Keeping that as a backdrop, collaborations and negotiations are constantly being launched to decide the particular trends and regions deserving support.
  • Preventive measures, diagnosis and control: There’s a conscious understanding that only path-breaking, long-term and disruptive innovations can transform the status quo of breast cancer, leading patients to a more personalized, faster and comprehensive form of care. It also helps to treat it early and fully. It becomes an imperative for cancer diagnosis to be early, proper and accurate. Gauging the signs and symptoms of breast cancer is important. Unfortunately, you cannot detect certain types of the disease early enough right now. There are some that are detected well within time, but the treatment becomes too heavy. It requires not only diagnostically advanced technologies and more advanced healthcare facilities, but also concerted and proactive involvement for patient/you.
  • The advanced case of Fluid biopsy: It entails a topmost rating amongst the technologies and advanced therapies to help achieve the coveted ‘moonshot’ of the disease. You require re-biopsies plenty of times during the treatment. It means deriving a new sample from the molding and an ever-changing tumor to demarcate the immediate therapy procedure. With the threadbare and current invasive biopsy procedures, patients and caregivers both face a massive challenge. With fluid biopsy patterns, you can extract the cancer cells from a simple, clear-cut and genuine blood sample.

You can find esteemed DNA sequencing companies who’ve announced a behemoth spin-off for create fluid biopsy solely, and making it commercial viable. It’s all set to be the next big thing in the genre of oncology.

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Be Calm and Composed in Your Cancer Treatment

Skin cancer happens to be the most common cancer in women but the immediate next is breast cancer. As per statistics, it’s a common phenomenon all across the world. Better and advanced knowledge of the breast cancer stages and treatment mean that more and more people can live full and long life after undergoing breast cancer treatment. The obvious pitfall is that the number of cases in the domain is on the rise. According to WHO, around 4, 400 women are diagnosed with the disease and 900 women die from it every year. It’s most common in women above 50 years of age but you can get breast cancer at a younger age too. The first prevention approach starts from checking and detecting the disease’s signs.

It’s the signs that lead you to the stages and subsequent treatment.  You need to perform dedicated and sincere breast care. That only comes from proper breast awareness.

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  • Deducing subtle and conspicuous changes: It’s important to understand that you need to be aware of a change in the formation, shape or size of your breasts. More often than not, it might so happen that one breast might become larger. Such irregularity is a tell-tale sign of breast cancer. Do notice if there are some changes in your nipple. They can develop change in the shape, direction or the way it is formed. Sometimes, it becomes pulled in, flattened or just inverted. There will be changes in and around the area of nipple and armpit as well. The skin may become flaky, crusted and very rash. You need to report it to your physician without delay.
  • The most conspicuous signs: On many occasions, the nipples discharge a fluid. It’s one of the clearest breast cancer symptoms. You might also experience recurring and intermittent pain in your armpit or one affected breast.
  • Ascertaining the causes: No amount of medication is suitable for the breast cancer stages and treatment if you can’t trace the disease to its roots. Till date, nobody has been able to decipher the exact causes behind this widespread disease. Contemporary researches have however showed numerous risk factors that lead to a woman’s scope of getting the cancer. Some of the risks are unfortunately beyond your comprehension and control. However, affirming them can help you take significant steps to protect yourself against it.
  • The stages and significance: Breast cancer entails many stages and there are dedicated treatments for each one of them. You start with diagnosis and biopsies and then to HER2 treatment. The rivabarim drug and herceptin are administered right from the initial stages.
  • Gender roles and age issues: Like it or not, women are prone to this disease and that’s a huge factor. The risk of cancer gets more as you get older. Studies reveal that most women suffer from it after crossing the age of 50.

Many times, women with a strong history of breast cancer in the family put are at an even risk of getting the disease. It includes breast cancer or/and ovarian cancer in different close same family members.

Helping a Breast Cancer Patient With Financial and Emotional Support

Since breast cancer is steadily on the rise in a fast-developing world, it becomes quite common for people to go for a solid treatment. If you have a look at it through a close lens, you will find that people are no longer afraid of the malignant disease, which is undeniably the most common form of cancer among the women worldwide. Life has to go on and there are so many working women diagnosed with the disease, who are taking the leap forward. All you need is proper care, emotional support and Cancer Financial Support sans crippling your daily life or work.

The simple thing starts with instilling some lifestyle changes and following proper guidelines and details regarding the treatment. Today, you don’t want to hamper work or duties and sit back at home, aggravating the mental stress. Medical and holistic breast treatment with related care is compulsory to bulwark HER2+ metastatic breast cancer treatment and also to support the cause.

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  • Beginning with emotional support: It goes beyond saying that cancer affects the patient and her family financially, psychologically and emotionally. But before assisting in finances, the first step will be to provide the correct treatment and information at the right time. The sheer objective is to give correct knowledge and guidance on facets related to breast cancer. You can find dedicated cancer society groups that provide great initiatives for patient support, helping patients and their family members understand the distress coming from disease and managing it.
  • Importance of emotional supprt: It’s an imperative to bear in mind that cancer and the resultant treatment is bound to create physical changes, big or small. Women suffering from breast cancer are naturally susceptible to experiencing depression, insecurity and may feel weak emotionally and physically. Each individual manages her feelings in a different manner. It depends on the medical and support systems available or provided to them. For those who enroll in cancer foundations and trusts, you will receive a great enrollment kit or bag that helps to counter the gross emotional stress that breast cancer creates. The kit carries things as simple and basic as little bag with wipes, moisturizer, shower cap, sanitizer, smuff or scarf and mirror. For cancer patients, these are important tools.
  • The financial support: Cancer Financial Support is available for those coming from weaker echelons of the society. It’s a known fact that the disease is a very prolonged and tedious, sometimes taking years to complete a treatment. It requires money on a recurring basis. There are dedicated hospitals that perform diagnosis and treatment either at extremely low-rates or free of cost. They give free and subsidized medicines to patients. The cancer support and welfare groups are doing a marvelous job in this regard. You need to give some details of your bank account to support your credentials.

Their doors are open for people with financial constraints to go with their ID proofs and income details. They will finance your treatment. There’s a huge network of compassionate and esteemed doctors doing this voluntary service. Humanity still exists and it’s here.

Carve Your Treatment Path From the Symptoms of Breast Cancer

While signs are little changes or irregular movements happening within the body, symptoms are the more vivid expression of the disease that’s developing inside. They are more conspicuous and you need to take heed of symptoms. It’s very important to know and check your breasts, and see how they look or feel. It defines breast health actually. In order to gauge the signs and symptoms of breast cancer and decide your treatment pathway, you need to be breast aware. That’s the fundamental requisite. Doctors urge women to be aware their breasts. By this they mean to take care of the subtle changes occurring, the normal feel and look of bosoms and any slight deviation that might happen due to breast cancer.

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Early diagnosis and treatment of the cancer means a much better chance to recover fully. You need to start the treatment right from home by taking proper breast care and being breast aware.

  • Seeing the most common things: There is no denying the fact that the most common symptom of breast symptom is a new mass formation or lump. . A painless, rigid and hard mass having irregular edges or formation is potentially breast cancer. However, these cancer types can also be soft or tender, even rounded. They can also be painful at times which makes it an imperative to visit a healthcare expert and esteemed cancer specialist. They can check any change or modification in the breast, breast mass or the newly formed lump. It’s the first step in diagnosing and treating the malaise.
  • Noting other like symptoms: The signs and symptoms of breast cancer include swelling of a breast’s part or the entire bosom. It can happen even if you don’t feel or see any distinct lump. May women experience dimpling in the region or skin irritation, which sometimes seems to be an orange peel. You might experience nipple or breast pain, conditioned with inward turning or movement of the nipples. It’s called nipple retraction. In this juncture, you feel thickening, redness and scaling of the breast skin or your nipple. On many occasions, there is nipple discharge, which is a form of liquid and not normal breast milk.
  • Symptoms and key aspects: You need to bear in mind that any of the concerned symptoms and signs mentioned can be due to other elements or physical factors other than cancer in your breast. Hence, if you detect the factors, you need to report that to your medic without delay. Considering the fact that mammograms cannot find or detect all breast cancer types, it’s an imperative for you to be aware of any change in your bosom. Proper knowledge, understanding and awareness is the key when you’re dealing with this malaise.
  • The auxiliary points: More often than not, a breast cancer has the capacity to spread to muscle mass or lymph nodes in your armpit region or the collarbone area. It can cause a swelling or lump in the area even before the original lump or baneful tumor in your breast is vivid and big enough to be felt and seen. You need to consult a doctor to test these swollen lymph nodes.

Discerning the Breast Cancer Stages to Affirm a Proper and Extensive Treatment

For anybody who has been diagnosed with breast cancer, you will probably come across various terms and terminologies describing the disease. Doctors use information and results from the breast biopsy report to underline a plethora of crucial information about the exact form of nature of cancer you’re suffering from. Patients may also need other tests to understand the information. But, before that, you need to understand the significance of breast cancer stages and treatment.

Only then you will know the frequency at which the malaise is developing. It will help you to chalk out the treatment plan. The concerned treatment entails various stages along with the collective efforts. Knowing each stage and what they offer is very important.

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  • The staging part: Once you’re diagnosed with breast cancer, the medical team will figure out how far it has spread and trace the origins. This pivotal process is called staging. You need to remember that the stage of your cancer helps determine the magnitude and complexity of the disease. It also makes way for the best methods to treat it. In this setup, the doctors address and highlight a few key things. Regardless of the invasive or non-invasive nature of the cancer, the size of the breast tumor and its spread to adjacent areas and whether the cancer has reached surrounding lymph nodes will be assessed. If the reports show an extension, then the doctors check the number involved.
  • Explaining a stage: Medics stage breast cancer treatment incorporating the AJCC or the American Committee of Cancer’s TNM method. It thrives on a three-fold piece of information. The first thing includes the breast tumor size, denoted by T. Its spread to nearby lymph nodes is marked by N. The condition of the disease becoming metastasized or spreading to other body parts is marked by M. You’ll find that the higher is the numbers, the more advanced is the malaise. After determining a patient’s TNM, they combine the details in a post-surgical method called stage grouping. It helps in determining and labeling an overall condition or stage.
  • The initial stages: The first stage cancers are called stage 0 and are marked by carcinoma in situ. They range from I-IV stages. You will find that some stages contain semi-phases of A, B and C and letters marking the extent. The lower the main number, the less is the development or growth of breast cancer. Stage IV is the advanced stage.
  • A stage and pathological inference: Your breast cancer stages and treatment depends on the spread and damage caused. The staging process can be very tedious and compound. Stage 0 is about DCIS, which is pre-cancer of the breast. Being the earliest stage, the cancer cells remain in the duct and don’t go deeper into the adjacent fatty bosom tissue. The upward climb starts from this point. Different stages and the sub-divisions have their own individual aspects. They show the extent of the cancer and the area it has spread to.

The fourth stage spreads to lymph nodes and other organs far from the M1 or your breast.

A Critical Assessment of the Financial Ambit and Needs of a Breast Cancer Therapy

Having financial constraints and worries are normal for a long treatment of breast cancer. The concerns may be temporary or permanent and it can be specifically draining at a time when you feel weak, helpless and fail to cope with cancer. The good news is that Cancer Financial Support is designed for you aid and all you need to do is utilize the benefits given to you by support groups. Availing the resources at the right time is the main thing.

The problem is many people, diagnosed with cancer are too reticent or embarrassed to ask for help or financial aid. Sometimes, they find the mechanism incongruous or too complicated. But, you need to know that you do have help and can avail the same, but in time.

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  • Knowing your rights: If you don’t have the capability to work due to the disease or the breast cancer therapy, you may be entitled to Statutory Sick Pay (SSP). You can speak to your HRD or director for this. Since the benefit can be compounding, you can take special help for financial constraints. Some hospitals provide welfare advisors and social case volunteers and health workers who can help you in this regard.
  • Cancer support groups: There are welfare groups producing booklets and spreading awareness for Cancer Financial Support meetings and programs. They make a clear underlining of the financial aid, ingrained benefits and provide suggestion to affected people. It also includes valuable details on housing cost benefits, conveyance and children’s requisites. You need to remember that not all diagnosis cases can claim these benefits. The concerned entitlement depends on individual circumstances. If you have secondary cancer, you may be entitled to obtain the aforementioned aid. You can fast track the benefits under the special rules criteria, which caters to terminally ill patients.
  • Allowance of care: You can find an array of employment benefit schemes and good insurance policies covering your critical illness. If you have any confusion, you should check with your HR head or insurance provider. Depending on the exact circumstances, your healthcare concern or caregiver may be entitled to claim the treatment-care allowance. They can give you the amount if you entail substantial requisites for needs.
  • Dedicated and licensed support groups: There are many groups licensed and approved by government authorities and international federations to provide cancer support. There are citizens advice group and cancer support society that advice and free aid. You can call them and they will tell you about all benefits and local government assistance or aid that’s available to you, family or other care-providers. They can also help you to fill out benefit claim applications.
  • The blue badge credence: It’s a practice available in a few countries and only a few governments can substantiate this provision. It’s a great scheme entailing extensive concessions in parking for patients with extreme mobility problems. They have difficulty in using public transport or commuting like others.

Women with secondary breast cancer have the eligibility to get a blue badge. The main symptoms are pain and fatigue.

Ushering in a New Dawn of Life With Timely and Proper Treatment For Breast Cancer

So many women out there experience succor and happiness after undergoing a comprehensive and successful treatment for breast cancer. The excitement and bliss is worth seeing. But, you should remember that it’s a worrisome time for women who anticipate a relapse of the disease. You might also feel helpless and lost without the same attendant care or weight of doctor victims from the healthcare clinic and medical teams. Even after you’re done with breast cancer treatment, your physician keeps a close surveillance. It’s most pivotal to perform follow-up care via scheduled appointments.

You need to discuss about all existing problems in the scheduled visits. The doctors may also undertake lab examinations or imaging tests for detecting side effects or other signs of cancer treatment.

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  • The mammogram tests: If you have undergone a breast-conserving test and surgery, the doctors will conduct a mammogram exam within 6-12 months after the completion of main surgery and radiation. You will receive the second test one year after the first exam. If you undergo a mastectomy test, you’ll need to have mammograms every year. It will include the other breast too.
  • Pelvic girdle tests: Post treatment for breast cancer, ushering in a new lease of life is smooth. But you need to be careful and cautious. If you’re taking any hormone drug and still continue having troubled uterus, you need to undergo pelvic tests each year. The main reason is that these drugs have the potential to aggravate the risk of uterine cancer. The risk reaches its zenith in those women who have crossed menopause. You need to ensure that you tell your doctor about any irregular or unusual vaginal bleeding. If you bleed between monthly periods and spot a change or derailment in your periods, then you must inform that without delay. It’s usually caused by something else and not cancer. However, it could well be first sign of uterine cancer.
  • Do check for side-effects: It’s important to know that almost all cancer treatments have some side effects. Some of them might last for 2-3 days only or continue for weeks, while some might span across many months. There are some side effects that don’t show up for many years after you complete the treatment. Routine doctor visits are a crucial thing to discuss about any issues or changes you discern in your body. You need to forth your concerns.
  • Other notable tests: Ancillary tests like imaging blood tests or bone scams and chest x-rays are more than a mere follow-up or standard medical process. There is no substantial evidence to show that these things have helped women undergoing breast cancer therapy to live longer. But you can still do them if you find physical test results or symptoms indicating a relapse of the cancer.

If you’re taking aromatase inhibitor and exemestane, anastrozole type of drugs in early stages of the breast cancer, or if you have crossed menopause during the course, your doctor will monitor the health of your bones and may also test its density.

Knowing The Most Popular Treatment Avenue for Breast Cancer

The most important thing is to know how cancel cells grow. They multiply and accumulate in an uncontrolled, gradual fashion. A very reliable and common treatment for breast cancer is Trastuzumab or Herceptin medication. It functions on the concerned cancer cell’s surface by blocking the chemical signals or disease-bearing agents that have the capacity to accelerate, stimulate or shield unbridled, unpredictable growth. The study of genes is also crucial in affirming the overall effectiveness of this drug in treating cancer. You can find instruction manuals showing how each cell of the human body grows, defining and describing what type of cell takes shape or grows in future, and precisely you should respond or behave.

Before going for treatment, it’s always pivotal to know that genes function by ordering human cells to locate and create special proteins that cause specific activities like rest, repair and cell growth.

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  • Focus on HER2: Some breast cancer cells have a tendency of over-expressing or cloning too many copies of a particular gene called HER2. This gene indicates the HER2 receptor, which is another vital protein. You need to know thatHER2 receptors are similar to your eyes, ears, and nose and are basically antennae on the body of cells. These specific HER2 receptors obtain signals that stimulate the cell to multiply or grow unabatedly. However, breast cancer cells with ceaseless HER2 receptors have the serious potential to pick up or block a cluster of harmful growth signals. As result of this function, they start to grow and multiply too fast and in huge numbers. Breast cancer cells over-expressing the concerned HER 2 gene are called Her2 positive.
  • Stick to basics: There are some cancer cells showing abnormalities in these genes. They tell the cells how much quotient you require and how fast it can grow. You will find that cancer cells replicate too many copes and clones of the abnormal, detrimental genes. That’s the basis of causing damage. When there are way too many copies of odd genes, doctors term the formulation as an over-expression. With certain folds of gene-over expression, you will find that cancer cells generating plenty of proteins and holding and controlling cell growth and division are the ones causing the diease to spread or grow.
  • The work of Herceptin: The drug works by attaching itself to the concerned HER 2 receptors on the cell surface of the breast cancer. The drug traps and blocks them from preventing any growth signal and by blocking the pathway of the signal; Herceptin can can slow down and stop the growth and formation breast cancer. It’s a classic example of a developed immune-based, targeted and systematic therapy. It blocks the the HER2 receptors or signal and can help fight the cancer. It alerts your immune system.
  • Having a cardiac test during the treatment course: Before starting this treatment for breast cancer, you need to undergo an echocardiogram test.

You can also have a multigated blood-pool imaging test or MUGA scan and test done to check the functional ability and state of your heart.

Riding on The Gold Standard of Cancer Care and Cure in India

To know about the way India is dealing with cancer, the inference of its pharmaceutical sector is very important. As per studies, the booming pharmaceutical industry is all set to touch and even cross $58 billion by 2020. It is currently making a dramatic transition to technological innovation and digitalization, and more qualitative research and development work with flurry of investments pumped in from all quarters are making it possible. The present market range is a staggering $27.59 billion and with large scale of breast cancer treatment drugs like Trastuzumab, the pharmaceutical sector is expected to break all records at an estimated pace of 15.92% growth.

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The country recently conducted some of its largest clinical trials and testing to measure the impact and efficiency of singular drugs against dual combination. It acts as a yardstick of HER2 positive breast cancer. The results were simply amazing.

  • The clinical findings: With Tykerb or lab name lapatinib not providing a conspicuous benefit to standard Trastuzumab or herceptin adjuvant treatment, researchers state that the current trials demonstrate a good old vanguard of the malaise remaining the same. Successive clinical tests from the trial’s phase III show that blending lapatinib with Trastuzumab and further syncingit with chemotherapy didn’t bolster patient outcome to a great degree. This particular thing is defined and highlighted as a disease free survival. You can also call it as an overall survival. Surprisingly enough, the drug lapatinib proved to significantly aggravate or raise the levels of toxicity in the body.
  • The immediate result: The clinical tests and results suggest that the consistent and persisting adjuvant post surgery and cancer therapy for the first-stage stage HER2 positive breast cancer must help Trastuzumab to remain in proper knitting with chemotherapy. The drug remains clinically the most effective and safe till date. Many Indian manufacturers supply this at cost-effective rates.
  • A renewed interest and work in the Bio-technology spectrum: The fact that many Indian pharmaceutical conglomerates are now in the prestigious race of making generic biosimilars/biologic drugs versions is indeed a matter of great pride. Biosimilars are extremely compound component to make but they provide a huge global landscape and capacity for the Indian companies to take their products to many untapped markets. Starting from 2008-09, the country’s biosimilar industry has been rapidly growing at a whopping 30% rate. In the ambit of cancer treatment alone, you have over thirty companies working in the biosimilar domain, marketing and packaging close to fifty or sixty products in the country’s local market itself.
  • The immediate impact: Today, patients in India have an extensive access to a host of crucial biosimilars like Insulin, analogues, Adalimumab, Rituximab and Filgrastim. Invariably, the early exposure and expertise in creating these drugs is actually paving the doorway of the next generation of cancer treatment and manufacturing of medicines.

The roads are opening more and more and a small glance of the pharmaceutical sector in the country will tell you how the ministry handles drugs and medicines.

Her2 Cancer: Life with Hertraz

All patients diagnosed with breast cancer need assessment of HER2 levels. HER2 cancer is more aggressive and spreads faster than other types of breast cancer. There is also more chance of recurrence with Her2 positive cancer within 5 years of treatment but with early diagnosis and correct treatment, this cancer is curable.

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What is HER2?

HER2 (human epidermal growth factor 2) is a gene that plays a role in development and progression of breast cancer. The HER2 gene makes HER2 proteins. These proteins are receptors on breast cells and are very sensitive to hormonal/chemical growth signals in the body.  More HER2 proteins than normal means they are receiving more signals to grow and divide than normal cells.

Tests for HER2

The Her 2 status of breast cancer is determined by tests called Immunohistochemistry (IHC) and Fluorescent in situ hybridization FISH biopsy.

HER 2 status helps in determining the grade of the tumor and the treatment modality. The treatment plan is a combination of surgery, chemotherapy, radiotherapy and targeted treatments. The oncologist will decide the treatment plan depending on the stage of cancer (size of a tumor and spread beyond the breast), grade (how fast the cancer cells are growing), whether the cancers cells HER2 positive, whether the cancer cells are positive for estrogen.

Targeted therapy drugs

The targeted treatments selectively block the HER2 from helping cancer cells grow. Unlike, chemotherapy medicines they don’t affect the normal cells.

Trastuzumab (Herceptin, Hertraz) blocks cancer cells from responding to chemical signals that trigger their growth.

Adotrastuzumab-emtansine (Kadcyla) is a combination of Trastuzumab with chemotherapy medicine Emtansine. The trastuzumab delivers Emtansine directly to cancer cells effectively killing the cancer cell from within. It has shown promising results in HER2 positive metastatic breast cancers.

Pertuzumab (Perjeta) is a monoclonal antibody that works by preventing the her2 binding with cancer cells, thus blocking their growth.

Lapatinib (Tykerb) works in a similar fashion as Trastuzumab and is given to patients with advanced breast cancers which overexpress HER2.

Nerlynx (Neratinib) is a once-daily oral medicine that works inside the cell to block pathways of HER2 positive cancer.

Side Effects of Targeted Therapy

Some people can have more side effects while undergoing this treatment. Hence, care should be taken.

  • Risk of developing a blood clot. Report to your physician if there is any swelling, redness, and pain in the leg, shortness of breath and pain in the chest.
  • Nausea and diarrhea can be managed with over the counter medicines.
  • Soreness at the injection site with subcutaneous hertraz injection.
  • Flu-like symptoms can manifest after the first dose. Take Ibuprofen or Acetaminophen to combat fever, body aches, and chills.
  • Risk of developing an abnormal heart rhythm which will manifest as palpitations and breathlessness. Usually, ECG is carried out before starting the treatment and repeated every 6 months to monitor the effect on the heart.

People with existing heart conditions are not prescribed hertraz.

These drugs have improved the survival rate of HER2 positive stage 1 to stage 3 breast cancers by more than 30%- a huge step forward in cancer cure.